Research & Development
Welcome to the Merck Frosst Centre for Therapeutic Research, the world-class biopharmaceutical research centre and drug discovery powerhouse of Merck Frosst Canada Ltd. the Canadian subsidiary of Merck & Co., Inc.
You are entering the scientific zone of our website. Here we showcase our research programs targeting the discovery of new treatments for respiratory and inflammatory diseases, as well as our work in exciting new areas of diabetes and obesity, cardiovascular and respiratory disorders.
The Merck Frosst Centre for Therapeutic Research is the largest private biomedical research facility in Canada and a premier laboratory in drug discovery. More than 225 scientists are based in the state-of-the-art research facility in Montréal, Quebec.
The Centre is divided into five research groups: Medicinal Chemistry, Biological Sciences, Process Chemistry, Pharmacology, and Pharmaceutical Research and Development. The R&D programs of the Merck Frosst Centre for Therapeutic Research are aimed at discovering novel and improved therapeutic agents for the treatment of respiratory, inflammatory and other diseases. The researchers at Merck Frosst are world leaders in leukotriene and prostaglandin research and have quickly built international reputations in other research areas.
Efforts in the leukotriene programs have yielded one highly effective and innovative medicine: the leukotriene D4 receptor antagonist SINGULAIR® (montelukast sodium) for bronchial asthma in adults and children as young as six. This is a highly effective once-a-day oral therapy.
While the Centre will continue to build on its success in leukotrienes and prostaglandins research, Merck Frosst scientists are also looking to new areas. Challenging projects aimed at the future benefit of patients include innovative work on new therapies for diabetes and obesity. Research is also continuing on other approaches to treatments for human bronchial asthma, and chronic obstructive pulmonary diseases.
The Merck Frosst Centre for Therapeutic Research is investing aggressively in bioinformatics, gene expression technology, drug candidate automated screening technologies, and research information technology, to increase productivity and speed the drug discovery process.
The vigorous research and development program at Merck Frosst has a ripple effect, stimulating scientific innovation across Canada. Through the funding of university and hospital-based science and other partnerships, Merck Frosst is helping to create an environment that attracts world-class science to Canada and keep it here.
We hope that all visiting scientists will enjoy our site. For those looking for the next step in their careers, we would encourage you to check out career opportunities with us. Merck Frosst is always interested in world-class scientists who wish to apply their talents to build on our legacy of success for a healthier tomorrow.
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