| 1. | Merck Frosst Canada - Pharmaceutical R&D Overview |
| | The Pharmaceutical Research and Development department at Merck Frosst has the task of turning the concept into reality, designing an appropriate dosage form to get the medicine from the bench to the patient.... The major area of expertise at the Research Centre is in solid oral dosage forms and it is also the main group within Merck worldwide that has aerosol formulation knowledge and experience.... |
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| 2. | Merck Frosst Canada - SINGULAIR® |
| | The final challenge for the scientists at Merck Frosst was finding a dosage form that was easy to take, especially for children.... |
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| 3. | Merck Frosst Canada - Materials Science |
| | In collaboration with, and, the researchers select the best physical form, based on the compound's bioavailability, physical and chemical stability, as well as how well it will process when the dosage forms are made.... |
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| 4. | Merck Frosst Canada - Analytical Research Laboratory |
| | The bio-analytical team, a part of the analytical group, evaluates the bioavailability of the new compound in several animal species, and also the delivery of the drug from formulated solid dosage forms.... These evaluation protocols also ensure the quality of dosage forms undergoing clinical trials.... |
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| 5. | Merck Frosst Canada - Clinical Supplies |
| | The Clinical Supplies department at the Merck Frosst Centre for Therapeutic Research prepares experimental dosage forms of all new drug candidates discovered in the Research Centre, to support clinical trials of the drug in humans.... The knowledge and experience gained in preparing these experimental dosage forms is part of the technology transfer that takes place from research to manufacturing in the run up to the launch of a new drug.... |
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| 6. | Merck Frosst Canada - Formulation and Process Development |
| | Formulation and Process DevelopmentWhen scientists at the Merck Frosst center for Therapeutic Research have identified a new chemical entity for development, the Formulation and Process Development group is responsible for developing the most appropriate dosage form, be it a tablet, capsule, oral solution, suspension, intravenous solution, lyophilized product or cream.. |
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