| | Merck Frosst Canada - Osteoarthritis of the Base of the Big Toe... Osteoarthritis of the base of the big toe, or metatarsophalangeal osteoarthritis, may be caused by an injury, a problem with how the foot is shaped, or a mechanical problem when walking.... When the joint moves, it may make a cracking noise, and you may be able to feel a bone spur or osteophyte at the base of the big toe, on top of the foot.... |