| 1. | Merck Frosst Canada - Biochemistry |
| | In a paper in Cell, the group described how these enzymes interact with beta amyloid precursor protein to damage neurons in Alzheimer's disease.... |
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| 2. | Merck Frosst Canada - Pharmacology |
| | Using this information, researchers can generate mice that serve as genetic disease models for disorders such as diabetes, arthritis and Alzheimer's disease.... The identification of mutations responsible for human illnesses ranging from Alzheimer's disease to diabetes have ushered in an exciting new era of pharmacology whereby drug discovery can now be performed using genetically relevant in vivo models.... |
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| 3. | Merck Frosst Canada - Bioinformatics |
| | By mining the human genome draft data, molecular biologists from Merck Frosst were able to identify several novel caspases, collectively representing a new target for neurodegenerative diseases such as Alzheimer's disease.... |
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| 4. | Merck Frosst Canada - Partners |
| | Current research and development programs at Merck laboratories focus on nine priority disease areas - Alzheimer's disease, atherosclerosis, cardiovascular disease, diabetes, novel vaccines, obesity, oncology, pain and sleep disorders.... Merck invested $ 3 million in an ultra-high field MRI scanner, which will help its researchers accelerate the study of a range of disorders, including respiratory illnesses, stroke and Alzheimer's disease.... |
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| 5. | Merck Frosst Canada - Our Research |
| | Merck has invested more than $ 20 billion to research heart disease, asthma and osteoporosis.And now we're trying to make diseases like Alzheimer's, diabetes and obesity history too.. Merck has 10 laboratories worldwide, one of which is the Merck Frosst Centre for Therapeutic Research, located in Montréal, Québec.. |
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| 6. | Merck Frosst Canada - Past and Present Research |
| | Alzheimer's Disease... |
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| 7. | Merck Frosst Canada - VIOXX® Information Center |
| | Our scientists are making real progress in early-stage research on such pressing unmet medical needs as diabetes, cancer, HIV / AIDS, obesity and Alzheimer's disease.... |
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| 8. | Merck Frosst Canada - VIOXX® Information Center |
| | Therefore, we promptly unblinded key safety data from two ongoing placebo-controlled trials in Alzheimer's disease (one trial for prevention of the disease, and one trial in patients with a mild form of the disease).... |
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| 9. | Merck Frosst Canada - Publication Lists |
| | Gervais F.G, D. Xu, G.S Robertson, J.P. Vaillancourt, Y. Zhu, JQ Huang, A. LeBlanc, D. Smith, M. Rigby, M.S Shearman, E.E Clarke, H. Zheng, L.H Van Der Ploeg, S.C. Ruffolo, N.A. Thornberry, S. Xanthoudakis, R.J Zamboni, S. Roy, and D.W Nicholson.. Involvement of caspases in proteolytic cleavage of Alzheimer's Beta-Amyloid precursor protein and amyloidogenic Beta-peptide formation.... |
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| 10. | Merck Frosst Canada - Partner of the Bell Science Fair |
| | At the Canada-Wide Science Fair, Wei Zhang and Yang Li, students at the Sir Winston Churchill High School in Calgary, won the Merck Frosst Award for their project on the mechanisms of neurodegeneration in Alzheimer's disease.... |
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